CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models
نویسندگان
چکیده
منابع مشابه
CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models.
Osteosarcoma is the most common bone tumors in children and adolescents. Despite intensive chemotherapy, patients with advanced disease still have a poor prognosis, illustrating the need for alternative therapies. In this study, we explored the use of antibodies that block CD47 with a tumor growth suppressive effect on osteosarcoma. We first found that up-regulation of CD47 mRNA levels in the t...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4282